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The T-box gene family encodes a large family of transcription factors with more than 20 members identified in humans so far, and homologues in many other organisms. A number of human disorders have been linked to mutations in T-box genes, confirming their medical importance. They include Holt- Oram syndrome/ TBX5, Ulnar-Mammary syndrome/ TBX3.
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By 2025, over 20 million passenger cars will be equipped with T-Box, and the installation rate will climb to 83.5%, and. T-Box and telematics are growing indispensable to passenger cars.
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cd00182 (PSSM ID: 410312): Conserved Protein Domain Family T-box, The T-box family is an ancient family of transcription factors which plays a multitude of diverse functions throughout development
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Abstract. The multi-chambered mammalian heart arises from a simple tube by polar elongation, myocardial differentiation and morphogenesis. Members of the large family of T-box (Tbx) transcription factors have been identified as crucial players that act in distinct subprogrammes during cardiac regionalization.Tbx1 and Tbx18 ensure elongation of the cardiac tube at the anterior and posterior.
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T-box proteins generally range in size from 50 kDa to 78 kDa. Brachyury, the founding member of the T-box gene family, has been shown to encode a sequence-specific DNA-binding protein that functions as a transcriptional activator [ 1, 14, 15, 16, 17 ].
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The T-box family of genes is among the most important developmental transcription factors present in Metazoa. This family is characterized by an evolutionary conserved DNA-binding domain of 180-200 amino acids, known as the T-box domain ( 1 - 3 ). Brachyury is the founding and best-characterized member of the T-box family, with well.
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T-Box (Telematics-Box), also called telematics control unit (TCU), is comprised of GPS unit, outer interfaces for communications, electronic processing units, microcontrollers, mobile.
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The word Yelek means a vest or waistcoat in modern Turkish, and that approximates the role of the Yelek in an Ottoman woman's wardrobe. It can be worn alone over a Gömlek and in the hot summertime. Or it can be worn under an Anteri for warmth or fashion.
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The S32K148-T-BOX is a reference design board engineered for out-of-the-box validated automotive telematics box (T-Box) applications. Based on the 32-bit Arm ® Cortex ®-M4F based S32K148 microcontroller, the S32K148-T-Box solution offers a flexible evaluation platform for the T-Box connected-car-standard terminal.The S32K148-T-Box solution is fully compatible with the S32K148EVB.
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AA1000 and AA1300 refer to AAA NiMH battery, which is also one of the commonly known as No.5 battery, 1000 and 1300 refer to the battery capacity, 1000 mAh and 1300 mAh respectively. Due to the harsh working environment of the car t-box battery, at present, the batteries used are basically NiMH batteries. This is also because at present only.
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Brachyury is the founder member of the T-box family of transcription factors, which is characterized by a DNA-binding domain of approximately 200 amino acids. Members of the T-box gene family play important roles in the development of both vertebrate and invertebrate embryos, including the control of gastrulation, development of the heart, and perhaps even the decision as to whether to form.
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T-box refers to a group of transcription factors involved in embryonic limb and heart development. [1] Every T-box protein has a relatively large DNA-binding domain, generally comprising about a third of the entire protein that is both necessary and sufficient for sequence-specific DNA binding.
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By EST database homology searching, Yi et al. (1999) identified a cDNA clone with a partial version of the T-box region. A composite cDNA that included sequence from a PAC, which the authors designated TBX19, encodes a 448-amino acid protein. Sequence analysis revealed that TBX19 is highly similar to the T gene protein product.
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Arrow Electronics launches proven Telematics reference design. T-Box penetration rate in the automotive market is growing rapidly, from 28.7% in 2018 to 32.5% in 2019. It is estimated that it will reach 43% in 2020 and 95% in 2025, becoming standard equipment for automobiles. The key factors are intelligence and the income of automobile.
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The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation. Nat. Cell Biol. 13 , 1084-1091 (2011).
